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Identificación de compuestos antibacterianos en macroalgas presentes en la Región del Biobío, Chile

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CORRESPONDING

Nicolás Troncoso

nicotroncoso@udec.cl

1

1

Grupo Interdisciplinario en Biotecnología Marina (GIBMAR), Centro de Biotecnología, Universidad de Concepción, Casilla 160-C, Concepción, Chile

Ricardo Saavedra

1

1

Grupo Interdisciplinario en Biotecnología Marina (GIBMAR), Centro de Biotecnología, Universidad de Concepción, Casilla 160-C, Concepción, Chile

Alex Olivares

1

1

Grupo Interdisciplinario en Biotecnología Marina (GIBMAR), Centro de Biotecnología, Universidad de Concepción, Casilla 160-C, Concepción, Chile

Jorge Farías

1

1

Grupo Interdisciplinario en Biotecnología Marina (GIBMAR), Centro de Biotecnología, Universidad de Concepción, Casilla 160-C, Concepción, Chile

Sergio San-Martín

1

1

Grupo Interdisciplinario en Biotecnología Marina (GIBMAR), Centro de Biotecnología, Universidad de Concepción, Casilla 160-C, Concepción, Chile

Homero Urrutia

2

2

Laboratorio de Biopelículas y Microbiología Ambiental, Centro de Biotecnología, Universidad de Concepción, Casilla 160-C, Concepción, Chile

Cristian Agurto

1

1

Grupo Interdisciplinario en Biotecnología Marina (GIBMAR), Centro de Biotecnología, Universidad de Concepción, Casilla 160-C, Concepción, Chile

Abstract

Several studies have been done in order to detect antibiotics from natural sources, seaweeds among them. With the aim of identifying antibacterial compounds, 5 species of seaweeds have been evaluated. The raw extracts were analyzed against bacteria, Gram-positive and negative, with diffusion discs and bioautography, then, they were characterized by GC-MS. The seaweeds Gracilaria chilensis, Ulva sp., and Macrocystis pyrifera present inhibition in the bacterial growth of tested strains. Three molecules, Phytol, 6-methyl-2-phenylquinoline and Neophytadiene were identified from Ulva sp. and M. pyrifera extracts. The results represent a potential use to incorporate these properties into biomaterials.

Key words

Antibacterial capacity, seaweeds, bioautography, biomaterials

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